What are the causes of Addison's disease (primary hypoadrenalism)?
Causes of Addison's disease (primary hypoadrenalism)
- Autoimmune adrenalitis
- TB
- HIV/AIDS
- Bilateral adrenalectomy
- Adrenal haemorrhage or infarction following meningococcal septicemia (Waterhouse-Friedrichson syndrome)
- Infiltration disorders:
- Carcinomatous infiltration of adrenal glands (bronchial carcinoma)
- Haemochromatosis
- Amyloidosis
- Granulomatous disorders
- Lymphoma
- Metyrapone therapy
- Schilder's disease (adrenal leukodystrophy)
- Wolman's disease (hepatosplenomegaly and steatorrhoea)
Source:
- Davidsons Principles and Practice of Medicine
23th edition: 671
- Kumar & Clark’s Clinical Medicine 9th
edition: 1226
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