What are the causes of Prolonged QT interval?
Prolonged QT interval:
The causes of the prolonged QT interval are followings:
Congenital causes of the prolonged QT interval:
- Jervell-Lange-Nielsen (JLN) syndrome: (includes deafness and is due to an abnormal potassium channel)
- Romano-Ward syndrome: (no deafness)
Drugs that Induce prolongation of QT interval:
- Amiodarone
- Sotalol
- Class 1a antiarrhythmic drugs
- TCA (e.g. amitriptyline) (˃SSRI)
- SSRI (especially citalopram, Sertraline)
- Lithium
- Methadone
- Chloroquine
- Mefloquine
- Terfenadine
- Macrolides: Erythromycin, Clarithromycin
- Levofloxacin
- Domperidone
- Ketoconazole
- Haloperidol
- Tacrolimus
Other causes:
- Electrolyte: Hypocalcaemia, Hypokalemia, Hypomagnesaemia
- Acute MI
- Myocarditis
- HOCM
- Hypothermia
- Subarachnoid haemorrhage
- Hypothyroidism
Source:
- https://litfl.com/qt-interval-ecg-library/
- Step Up to MRCP Review note for Part 1 and 2 by By Dr Khaled El Magraby; page: 8
0 Comments